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. 2024 Jun 13;21:138. doi: 10.1186/s12985-024-02410-1

Table 1.

Proportion of patients developing IgG antibodies and neutralizing capacity against SARS-CoV-2 after infection and vaccination

Infected Vaccinated
N N (%) N N (%) p-value
IgG antibodies against RBD
 Overall 69 65 (94.2) 326 260 (79.7) 0.004
 KTR 22 19 (86.4) 129 72 (55.8) 0.007
 HD 24 23 (95.8) 85 76 (89.4) 0.45
 Control 23 23 (100.0) 112 112 (100.0) *
IgG antibodies against S1S2
 Overall 69 65 (94.2) 326 248 (76.1) 0.001
 KTR 22 19 (86.4) 129 60 (46.5) 0.001
 HD 24 23 (95.8) 85 76 (89.4) 0.45
 Control 23 23 (100.0) 112 112 (100.0) -
IgG antibodies against NP
 Overall 69 66 (95.7) NA
 KTR 22 20 (90.9) NA
 HD 24 23 (95.8) NA
 Control 23 23 (100.0) NA
Neutralizing capacity
 Overall 69 62 (89.9) 152 145 (95.4) 0.14
 KTR 22 20 (90.9) 21 17 (80.9) 0.41
 HD 24 23 (95.8) 24 21 (87.5) 0.61
 Control 23 19 (82.6) 107 107 (100.0) 0.001

Table showing the proportion of patients who developed IgG antibodies against RBD, the S1S2 domain of SARS-CoV-2, NP and neutralizing capacity. Numbers highlighted in bold indicate statistical significance. KTR Kidney transplant recipients; HD hemodialysis; RBD receptor binding domain, NP nucleocapsid protein. *no variation