Table 2.
IgG antibody titres against SARS-CoV-2 in responders after infection and vaccination
| Infected | Vaccinated | ||||
|---|---|---|---|---|---|
| N | Median [IQR] | n | Median [IQR] | p-value | |
| IgG antibodies against RBD | |||||
| Overall | 65 | 18.23 [9.38; 20.05] | 260 | 19.33 [16.05; 20.90] | 0.02 |
| KTR | 19 | 18.28 [12.97; 20.13] | 72 | 10.85 [3.07; 18.72] | 0.02 |
| HD | 23 | 16.82 [8.14; 20.46] | 76 | 17.07 [15.68; 19.23] | 0.77 |
| Control | 23 | 16.29 [9.30; 19.62] | 115 | 19.93 [19.54; 22.44] | < 0.001 |
| IgG antibodies against S1S2 | |||||
| Overall | 65 | 16.96 [10.32; 22.29] | 248 | 16.64 [8.40; 21.34] | 0.27 |
| KTR | 19 | 15.49 [9.33; 21.92] | 60 | 5.85 [1.89; 12.27] | < 0.001 |
| HD | 23 | 19.01 [12.97; 23.35] | 76 | 14.97 [6.75; 19.88] | 0.009 |
| Control | 23 | 15.13 [7.11; 20.50] | 112 | 20.57 [16.07; 22.16] | 0.004 |
| IgG antibodies against NP | |||||
| Overall | 66 | 35.10 [12.97; 38.27] | NA | ||
| KTR | 20 | 20.70 [8.30; 36.78] | NA | ||
| HD | 23 | 35.81 [33.15; 39.11] | NA | ||
| Control | 23 | 34.51 [15.10; 37.87] | NA | ||
Table showing the titres (median values, signal/noise ratio) of IgG antibodies directed to RBD, S1S2 and NP of SARS-CoV-2 in responders. Time from PCR or first vaccine to blood sample was not correlated with the IgG RBD titres (n = 248, rs = 0.04, p = 0.50) while it was weakly correlated with the IgG S1S2 titres (n = 236, rs = 0.17, p = 0.01). KTR Kidney transplant recipients, HD hemodialysis