FIG. 1.

Amino acid sequences of the CT domains of wild-type HSV-1, F-gESer, and F-gEΔCT. A portion of the 105-residue CT domain of gE is depicted, including two YXXØ motifs (underlined) and three serine residues at positions 478, 479, and 481 (boldface) that are flanked on the C-terminal side by a cluster of acidic residues (italic). In F-gESer, the three serine residues were changed to alanine residues. F-gEΔCT contains two stop codons (stars) C terminal to three arginine residues that flank the transmembrane domain (TMD; outlined letters).