Table A1.
Deltas EQ-5D-5L and EORTC QLQ-C30.
| HRQoL | Delta 1 (n = 333) |
Delta 2 (n = 333) |
|---|---|---|
| EQ-5D-5L | ||
| Index | ||
| Mean (SD) | −0.054 (0.158) | −0.032 (0.182) |
| Median [Min, Max] | −0.035 [−0.593, 0.503] | 0 [−0.702, 0.503] |
| VAS score | ||
| Mean (SD) | −3.69 (18.5) | −1.89 (18.2) |
| Median [Min, Max] | −1.00 [−69.0, 54.0] | 0 [−74.0, 55.0] |
| EORTC QLQ-C30 | ||
| Global Quality of Life scale | ||
| Mean (SD) | −2.53 (18.9) | −0.476 (19.9) |
| Median [Min, Max] | 0 [−66.7, 83.3] | 0 [−75.0, 66.7] |
| Emotional functioning | ||
| Mean (SD) | 4.36 (23.9) | 7.83 (23.6) |
| Median [Min, Max] | 8.33 [−75.0, 91.7] | 8.33 [−75.0, 83.3] |
| Role functioning | ||
| Mean (SD) | −9.36 (29.1) | −4.25 (29.1) |
| Median [Min, Max] | 0 [−100, 100] | 0 [−100, 100] |
| Physical functioning | ||
| Mean (SD) | −5.63 (14.5) | −3.14 (13.7) |
| Median [Min, Max] | −6.66 [−66.7, 60.0] | 0 [−66.7, 66.7] |
| Cognitive functioning | ||
| Mean (SD) | −7.66 (21.8) | −4.85 (21.0) |
| Median [Min, Max] | 0 [−100, 66.7] | 0 [−83.3, 66.7] |
| Social functioning | ||
| Mean (SD) | −6.81 (24.9) | −2.65 (24.1) |
| Median [Min, Max] | 0 [−100, 100] | 0 [−100, 66.7] |
| Fatigue | ||
| Mean (SD) | 8.88 (25.1) | 2.50 (23.0) |
| Median [Min, Max] | 11.1 [−88.9, 88.9] | 0 [−77.8, 77.8] |
| Nausea and vomiting | ||
| Mean (SD) | −0.250 (15.1) | −1.30 (13.9) |
| Median [Min, Max] | 0 [−66.7, 83.3] | 0 [−83.3, 50.0] |
| Pain | ||
| Mean (SD) | 7.41 (25.1) | 6.11 (23.4) |
| Median [Min, Max] | 0 [−83.3, 83.3] | 0 [−83.3, 100] |
| Dyspnea | ||
| Mean (SD) | 6.51 (24.3) | 2.50 (19.8) |
| Median [Min, Max] | 0 [−100, 100] | 0 [−100, 66.7] |
| Insomnia | ||
| Mean (SD) | 0.901 (31.3) | −1.90 (32.3) |
| Median [Min, Max] | 0 [−100, 100] | 0 [−100, 100] |
| Appetite loss | ||
| Mean (SD) | −4.80 (24.8) | −7.71 (22.6) |
| Median [Min, Max] | 0 [−100, 100] | 0 [−100, 66.7] |
| Constipation | ||
| Mean (SD) | 1.10 (22.6) | 0.801 (21.5) |
| Median [Min, Max] | 0 [−100, 100] | 0 [−100, 100] |
| Diarrhea | ||
| Mean (SD) | −1.80 (18.2) | −2.10 (17.7) |
| Median [Min, Max] | 0 [−100, 66.7] | 0 [−100, 66.7] |
| Financial difficulties | ||
| Mean (SD) | 4.50 (20.3) | 2.80 (19.3) |
| Median [Min, Max] | 0 [−100, 100] | 0 [−100, 100] |
| Summary score | ||
| Mean (SD) | −3.31 (13.0) | −0.459 (12.7) |
| Median [Min, Max] | −1.97 [−62.4, 40.9] | 0 [−48.0, 48.1] |
Note: delta 1, difference in scores between T0 and T6; delta 2, difference in scores between T0 and T12. Bold indicates delta > MCID of the EQ-5D-5L (0.08) or the EORTC QLQ-C30 (5).