Table 1.
Characteristics of SNC cases registered in the ReNaTuNS database (period: 1989–2022).
| Variable | Men N (%) |
Women N (%) |
|---|---|---|
| Sex | 2073 (73) | 778 (27) |
| Age, years (mean ± SD) | 67 ± 12.4 | 66.0 ± 15.2 |
| Age class | ||
| 0–44 | 104 (5) | 82 (11) |
| 45–54 | 230 (11) | 92 (12) |
| 0–54 | 334 (16) | 174 (22) |
| 55–64 | 460 (22) | 142 (18) |
| 65–74 | 639 (31) | 195 (25) |
| 75+ | 640 (31) | 267 (34) |
| 55+ | 1739 (84) | 604 (78) |
| Topography (ICD-X codes) | ||
| Nasal cavities (C30.0) | 1204 (50) | 452 (50) |
| Maxillary sinus (C31.0) | 420 (17) | 220 (24) |
| Ethmoidal sinus (C31.1) | 583 (24) | 146 (16) |
| Frontal sinus (C31.2) | 48 (2) | 14 (2) |
| Sphenoidal sinus (C31.3) | 113 (5) | 51 (6) |
| Overlapping lesion of accessory sinuses (C31.8) | 19 (1) | 8 (1) |
| Accessory sinus, unspecified (31.9) | 32 (1) | 10 (1) |
| Histology (a) | ||
| Adenocarcinomas | ||
| ITAC | 678 (33) | 74 (10) |
| Non-ITAC | 93 (5) | 42 (6) |
| AD NOS | 160 (8) | 26 (3) |
| SGC | 112 (6) | 108 (14) |
| Squamous cell carcinomas | ||
| SCC | 730 (36) | 376 (50) |
| Neuroendocrine carcinomas | ||
| NEC | 43 (2) | 21 (3) |
| Other epithelial neoplasms | ||
| SNC NOS | 108 (5) | 49 (6) |
| SNUC | 114 (6) | 57 (8) |
| Malignant Neoplasm | 16 (1) | 9 (1) |
(a) AD NOS, adenocarcinoma not otherwise specified; ITAC, intestinal-type adenocarcinoma; NEC, neuroendocrine carcinoma; non-ITAC, non-intestinal-type adenocarcinoma; SCC, squamous cell carcinoma; SNC NOS, sinonasal carcinomas not otherwise specified; SGC, salivary gland carcinoma; SNUC, sinonasal undifferentiated carcinoma.