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. 2024 May 28;16(11):2048. doi: 10.3390/cancers16112048

Table 2.

Diagnostic parameters for each classifier model according to cohort. AUC, sensitivity, specificity, and PPV/NPV were calculated for each predictor using published cut-off values.

Predictor Published Cut-Off Menopausal Status n= AUC (95%CI) Sensitivity % Specificity % PPV % NPV %
Ultrasound combined 169 0.77 (0.70–0.85) 63.2% 87.1% 76.8% 77.9%
1 or 4 pre 66 0.87 (0.74–10.0) 50.0% 98.0% 88.9% 86.0%
post 103 0.72 (0.62–0.82) 67.3% 76.5% 74.5% 69.6%
RMI2 score combined 169 0.95 (0.93–0.98) 90.2% 85.2% 66.1% 96.5%
≥200 pre 66 0.98 (0.94–1.00) 85.7% 94.9% 66.7% 98.2%
post 103 0.94 (0.89–0.98) 88.9% 77.6% 68.1% 92.9%
combined 169 0.99 (0.98–1.00) 91.1% 95.6% 91.1% 95.6%
MMP index ≥3.648 pre 66 0.97 (0.94–1.00) 85.7% 94.9% 66.7% 98.2%
post 103 0.99 (0.97–1.00) 92.0% 98.1% 97.9% 92.9%
MMP Index + Ultrasound combined 169 0.98 (0.97–1.00) 91.2% 96.4% 92.9% 95.6%
n/a pre 66 0.97 (0.93–1.00) 85.7% 94.9% 66.7% 98.2%
post 103 0.99 (0.97–1.00) 92.0% 98.1% 97.9% 92.9%