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Representative immunohistochemical staining of MMR proteins in tumors. Expression of MutL homolog 1 (MLH1), MutS homolog 2 (MSH2), MutS homolog 6 (MSH6), and PMS1 homolog 2 (PMS2) in formalin-fixed paraffin-embedded (FFPE) tissue samples identified as normal expression (top row, labeled as high) and loss of staining (bottom row, labeled as low); magnification, 20×.
