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. Author manuscript; available in PMC: 2024 Nov 1.
Published in final edited form as: J Steroid Biochem Mol Biol. 2023 Sep 15;234:106399. doi: 10.1016/j.jsbmb.2023.106399

Table 2. Expression of steroid hormone receptors PR and ER by immunohistochemistry in tumor tissue from which patient-derived organoid models were created.

Cases are organized by histologic subtype and stage/grade. Cases that were utilized for analysis of progesterone-mediated gene expression changes are underlined, whereas cases that were included in drug testing studies are italicized. N.D.: not determined; no tumor: no tumor cells were present for analysis in the stained slide.

Modified H-Score
Patient ID Histologic subtype Stage Grade PR ER
ONC-6885 Endometrioid IA 1 300 190
ONC-7756 Endometrioid IA 1 300 170
ONC-6790 Endometrioid IA 1 300 300
ONC-6818 Endometrioid IA 1 300 300
ONC-6692 Endometrioid IA 1 285 285
ONC-8743 Endometrioid IA 1 225 195
ONC-8004 Endometrioid IA 1 165 185
ONC-7076 Endometrioid IA 1 160 285
ONC-6096 Endometrioid IA 1 140 185
ONC-8734 Endometrioid IA 1 105 70
ONC-6844 Endometrioid IA 1 70 277.5
ONC-7723 Endometrioid IA 1 30 240
ONC-6932 Endometrioid IA 1 0 175
ONC-7026 Endometrioid IA 2 90 277.5
ONC-6498 Endometrioid IA 2 70 285
ONC-6173 Endometrioid IA 2 7.5 180
ONC-6051 Endometrioid IA 2 0 0
ONC-6925 Endometrioid IA 3 0 0
ONC-6191 Endometrioid IB 1 155 300
ONC-7787 Endometrioid IB 1 150 300
ONC-7677 Endometrioid IB 1 45 255
ONC-5768 Endometrioid IIIC2 1 110 292.5
ONC-7623 Serous IB 45 70
ONC-6720 Serous IIIC1 0 0
ONC-7991 Serous IV 45 217.5
ONC-6099 Serous IVB 0 0
ONC-7757 Clear cell IV 70 30
ONC-7367 Mixed clear cell & endometrioid IB 3 225 285
ONC-6742 Mixed serous & endometrioid IA 285 300
ONC-7003 Mixed serous & endometrioid IA 85 300