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. 2024 Jun 3;14(11):1176. doi: 10.3390/diagnostics14111176

Table 4.

Pleural fluid biochemistry (and blood/pleural fluid ratios), and pre-thoracentesis ultrasonographic findings.

Non-Expandable Lung
n =12
Expandable Lung
n =31
p-Value
Biochemistry
Pleural fluid protein, g/L 34.6 (11.5) 40.7 (10.9) 0.22
Pleural fluid albumin, g/L 17.1 (9.5) 23.1 (6.2) 0.058
Plasma albumin, g/L 31.0 (8.1) 28.5 (4.4) 0.30
Albumin gradient, g/L 10.8 (2.3) 6.3 (5.8) 0.080
Pleural fluid LDH, U/L 360 (284–1724) 165 (121–225) 0.007
Serum LDH, U/L 189 (180–190) 200 (170–270) 0.16
LDH gradient, U/L 7.3 (8.6) 1.2 (1.3) 0.015
Pre-thoracentesis ultrasound
Pleural fluid swirling, n (%) 3 (25%) 18 (58%) 0.052
Pleural fluid septations, n (%) 6 (50%) 3 (10%) 0.004
Pleural thickening, n (%) 10 (83%) 20 (65%) 0.23
Pleural nodules, n (%) 3 (25%) 8 (26%) 0.96
Atelectasis/consolidation, n (%) 7 (58%) 16 (52%) 0.21
Lung sliding, n (%) 2 (18%) 20 (65%) 0.008
Post-thoracentesis ultrasound
Apposition of pleural lines, n (%) 1 (9%) 22 (73%) <0.001
US assessed full drainage, n (%) 2 (18%) 19 (63%) 0.010

Data are presented as mean (SD) or median (IQR). LDH; Lactate Dehydrogenase. Gradient (blood concentration minus pleural fluid concentration).