Table 2.

Clinico-pathological and biomarker correlations of CD163 and CD206 TAM distance from tumor nest.

Features		sCD163		sCD206
		LO	HI	LO	HI
Clinico-pathological features
Age	Mean	49.4	47.9	47.5	49.4
	SD	10.1	10.1	10.0	10.3
	Median	48.0	46.0	45.0	48.0
	IQR	42–48	41–54	40–53	43–56
	Range	30–75	29–82	29–75	29–82
	p	0.208		0.121
Size	Mean	2.33	1.81	2.15	2.02
	SD	1.40	0.91	1.34	1.10
	Median	1.90	1.70	1.80	1.80
	IQR	1.4–2.9	1.3–2.2	1.2–2.6	1.4–2.3
	Range	0.2–7.6	0.1–5.6	0.2–7.0	0.1–7.6
	p	0.010		0.964
TIL	Low	84	86	84	84
	High (>20)	24	23	23	24
	p	0.841		0.897
Fibrotic focus	No	94	89	93	89
	Yes	14	20	14	19
	p	0.275		0.359
Necrosis	No	79	79	84	74
	Yes	29	30	23	34
	p	0.912		0.097
Apocrine	No	100	95	99	95
	Yes	8	14	8	13
	p	0.185		0.260
Grade	1	5	10	10	4
	2	54	64	57	63
	3	49	35	40	41
	p	0.028		0.438
LVI	No	95	98	95	95
	Yes	13	10	11	13
	p	0.508		0.700
LN met	No	61	55	65	52
	Yes	45	50	39	53
	p	0.451		0.059
Subtype	Lum A	24	25	28	22
	Lum B	62	59	61	58
	HER2-OE	10	10	6	12
	TNBC	12	13	10	16
	p	0.988		0.247
Biomarkers
Ki67	Lo	29	33	32	31
	Hi	78	74	72	77
	p	0.547		0.742
HER2	Neg	90	95	94	92
	Pos	17	13	11	16
	p	0.415		0.341
EGFR	Neg	106	104	105	103
	Pos	1	4	0	5
	p	0.369		0.060
ER	Neg	25	25	18	31
	Pos	82	81	86	76
	p	0.970		0.045
PR	Neg	24	27	17	33
	Pos	81	80	87	73
	p	0.686		0.012
c-kit	Neg	98	98	98	97
	Pos	9	11	9	10
	p	0.670		0.810
P63	Neg	94	100	100	94
	Pos	14	8	7	13
	p	0.177		0.159
CK5/6	Neg	91	88	94	84
	Pos	16	21	13	23
	p	0.400		0.068
CK14	Neg	100	102	100	100
	Pos	7	7	6	8
	p	0.971		0.605
PDL1ic	Neg	69	75	73	70
	Pos	38	34	34	38
	p	0.501		0.596
PDL1T	Neg	89	87	90	83
	Pos	14	10	9	16
	p	0.475		0.134
sCD163 density	Lo	46	61	51	52
	Hi	61	47	51	55
	p	0.048		0.839
tCD163 density	Lo	40	67	45	58
	Hi	67	41	57	49
	p	<0.001		0.145
sCD206 density	Lo	49	48	49	50
	Hi	52	53	56	51
	p	0.888		0.684
tCD206 density	Lo	45	68	51	63
	Hi	56	33	54	38
	p	0.001		0.045