Figure 5.

Histological grading of inflammatory activity according to the Robarts Histopathology Index (RHI) at t0, t1 and t2 time points. The t0 shows a high level of inflammation with distorted and scattered crypts (dashed lines). A larger number of neutrophilic granulocytes in the superficial epithelium (black arrowheads), in the intestinal crypts where they accumulate and form abscesses (*), and in the lamina propria were detected at t0, compared with t1 and t2. Haematoxylin and eosin (E&E) staining, O.M. X100, scale bar: 250 μm.