Table 1.
Characteristics of the IBD patients and healthy controls. Characteristics of the 19 patients with active ulcerative colitis (UC), 4 patients with active Crohn’s disease (CD) and 26 healthy controls included in the study. * According to the Montreal classification [21]. Mayo endoscopic score (MES); Harvey Bradshaw Index (HBI) score; Simple Endoscopic Score-Crohn Disease (SES-CD); N/A: not applicable.
| UC | CD | Healthy Controls | |
|---|---|---|---|
| Age, media (range) | 48 (22–81) | 47 (25–76) | 51 (41–69) |
| Gender | 7 women, 12 men | 2 women, 2 men | 13 women, 13 men |
| Current smokers, n (%) | 4 (21%) | 0 (0%) | 6 (23%) |
| Disease duration (mean months) | 32 (6–91) | 58 (52–61) | N/A |
| Location and behavior * | E2 11/19 (42.1%) E3 8/19 (57.9%) |
L2 B1 2/4 (50%) L3 B1 2/4 (50%) |
N/A |
| MES, median (range) | 2.5 (2–3) | N/A | N/A |
| Total Mayo Score, median (range) | 7.57 (5–11) | N/A | N/A |
| HBI score, median (range) | N/A | 7 (5–10) | N/A |
| SES-CD, median (range) | N/A | 7 (4–16) | N/A |
| Previous anti-inflammatory medication | Naïve to anti-TNFα (n = 5) Refractory to anti-TNFα (n = 14) |
Naïve to anti-TNFα (n = 3) Refractory to anti-TNFα (n = 1) |
N/A |