Table 1.

Inhibitory profile of ITF7209, ITF7738, and ITF7739 on HDACs.

HDACs IC50, nM
Compounds	zHDAC6-CD2	HDAC6	HDAC1
ITF7209	6.7 ± 0.4	7.2 ± 0.6	N.A.
ITF7738	(72 ± 2) × 103	N.A.	N.A.
ITF7739	(1.0 ± 0.1) × 103	(5.1 ± 0.2) × 103	N.A.
ITF5924 a	7.8 ± 0.4	7.7 ± 0.3	N.A.
ITF6715 a	(2.3 ± 0.1) × 103	(1.6 ± 0.1) × 103	N.A.
ITF6712 a	(9.7 ± 0.4) × 10	(3.3 ± 0.1) × 102	N.A.

N.A.: not active (IC₅₀ > 100 µM). ^a Data from [22] are included for comparison.