Skip to main content
. 2024 May 31;25(11):6082. doi: 10.3390/ijms25116082

Table 1.

Cohort characteristics of 40 patients with locally advanced esophageal squamous cell carcinoma treated with radiotherapy.

N % OS PFS
p p
Age (year) 0.108 0.040
 ≥65 18 45.0
 <65 22 55.9
KPS 0.019 0.014
 ≥90 17 42.5
 <90 23 57.5
Stage (AJCC 6th) 0.064 0.035
 I–II 8 20.0
 III–IV 32 80.0
Location 0.392 0.128
 Cervical and upper 8 20.0
 Middle and lower 32 80.0
Length 0.016 0.001
 ≤5 cm 18 45.0
 >5 cm 22 55.0
Primary tumor volume 0.019 0.007
 ≤50 cm3 18 45.0
 >50 cm3 22 55.0
Therapeutic approach 0.838 0.610
 RT 19 47.5
 CRT (Single) 7 17.5
 CRT (Doublet) 14 35.0
Response 0.566 0.758
 ORR 20 50.0
 SD 14 35.0
 PD 1 2.5
 NA 5 12.5
Fold change in miR-143-3p 0.872 0.443
 ≤1.5 27 67.5
 >1.5 13 32.5
Fold change in miR-181a-5p 0.382 0.833
 ≤1.5 19 47.5
 >1.5 21 52.5
Fold change in miR-223-3p 0.069 0.128
 ≤1.5 24 60.0
 >1.5 16 40.0
Fold change in miR-143-3p and miR-223-3p 0.024 0.008
 Both ≤ 1.5 20 50.0
 Any one > 1.5 and both > 1.5 20 50.0
Fold change in miR-143-3p and miR-181a-5p 0.318 0.456
 Both ≤ 1.5 18 45.0
 Any one > 1.5 and both > 1.5 22 55.0
Fold change in miR-181a-5p and miR-223-3p 0.034 0.401
 Both ≤ 1.5 15 37.5
 Any one > 1.5 and both > 1.5 25 62.5