Age (year) |
|
|
0.108 |
0.040 |
≥65 |
18 |
45.0 |
|
|
<65 |
22 |
55.9 |
|
|
KPS |
|
|
0.019 |
0.014 |
≥90 |
17 |
42.5 |
|
|
<90 |
23 |
57.5 |
|
|
Stage (AJCC 6th) |
|
|
0.064 |
0.035 |
I–II |
8 |
20.0 |
|
|
III–IV |
32 |
80.0 |
|
|
Location |
|
|
0.392 |
0.128 |
Cervical and upper |
8 |
20.0 |
|
|
Middle and lower |
32 |
80.0 |
|
|
Length |
|
|
0.016 |
0.001 |
≤5 cm |
18 |
45.0 |
|
|
>5 cm |
22 |
55.0 |
|
|
Primary tumor volume |
|
|
0.019 |
0.007 |
≤50 cm3
|
18 |
45.0 |
|
|
>50 cm3
|
22 |
55.0 |
|
|
Therapeutic approach |
|
|
0.838 |
0.610 |
RT |
19 |
47.5 |
|
|
CRT (Single) |
7 |
17.5 |
|
|
CRT (Doublet) |
14 |
35.0 |
|
|
Response |
|
|
0.566 |
0.758 |
ORR |
20 |
50.0 |
|
|
SD |
14 |
35.0 |
|
|
PD |
1 |
2.5 |
|
|
NA |
5 |
12.5 |
|
|
Fold change in miR-143-3p |
|
|
0.872 |
0.443 |
≤1.5 |
27 |
67.5 |
|
|
>1.5 |
13 |
32.5 |
|
|
Fold change in miR-181a-5p |
|
|
0.382 |
0.833 |
≤1.5 |
19 |
47.5 |
|
|
>1.5 |
21 |
52.5 |
|
|
Fold change in miR-223-3p |
|
|
0.069 |
0.128 |
≤1.5 |
24 |
60.0 |
|
|
>1.5 |
16 |
40.0 |
|
|
Fold change in miR-143-3p and miR-223-3p |
|
|
0.024 |
0.008 |
Both ≤ 1.5 |
20 |
50.0 |
|
|
Any one > 1.5 and both > 1.5 |
20 |
50.0 |
|
|
Fold change in miR-143-3p and miR-181a-5p |
|
|
0.318 |
0.456 |
Both ≤ 1.5 |
18 |
45.0 |
|
|
Any one > 1.5 and both > 1.5 |
22 |
55.0 |
|
|
Fold change in miR-181a-5p and miR-223-3p |
|
|
0.034 |
0.401 |
Both ≤ 1.5 |
15 |
37.5 |
|
|
Any one > 1.5 and both > 1.5 |
25 |
62.5 |
|
|