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. 2024 May 29;25(11):5965. doi: 10.3390/ijms25115965

Table 3.

Lipids enhanced the classification of NASH patients as derived from the XGBoost algorithm.

Total Population NASH Control–NAFL
p-Value Median 95% Lower CI 95% Upper CI Median 95% Lower CI 95% Upper CI Median 95% Lower CI 95% Upper CI
HOMA-IR 2.61 × 10−4 3.50 2.20 4.80 6.10 4.80 8.95 2.2 1.70 2.90
BMI (kg/m2) 1.04 × 10−2 29.3 25.7 31.2 31.6 28.5 35.3 26.0 24.4 30.4
Platelets (×103) (K/μL) 1.87 × 10−1 226 205 251 216 172 253 226 207 274
LDL (mg/dL ) 8.10 × 10−1 101 82.0 121 96.0 80.0 121 101 77.0 126
Ferritin (ng/mL) 2.62 × 10−2 149 98.7 218 200 132 569 101 76.0 163
AST (U/L) 8.47 × 10−5 27.0 23.0 35.0 43.5 35.5 52.5 22.0 20.0 27.0
FA 12:0 (μΜ) 5.50 × 10−4 73.4 71.7 74.0 75.2 73.8 86.7 71.7 71.2 73.4
FA 18:3 ω3 (μΜ) 1.11 × 10−3 66.0 65.2 68.9 70.8 66.9 81.5 65.3 64.7 66.0
FA 20:4 ω6/
FA 20:5 ω3
4.79 × 10−1 5.86 5.74 6.14 5.79 5.51 6.20 5.92 5.66 6.27
CAR 4:0 (μΜ) 4.18 × 10−1 0.09 0.07 0.11 0.11 0.09 0.13 0.07 0.07 0.11
LPC(20:4) (μΜ) 9.60 × 10−3 7.99 6.71 8.75 6.16 5.07 7.81 8.66 7.99 9.76
LPC(O-16:1) (μΜ) 3.25 × 10−1 0.74 0.68 0.85 0.73 0.67 0.86 0.77 0.67 1.00
LPE(18:0) (μΜ) 7.95 × 10−2 2.43 1.97 2.86 2.53 2.28 3.44 2.02 1.90 2.88
DG(18:1_18:2) (μΜ) 8.19 × 10−3 15.2 12.6 18.0 22.0 17.5 35.2 13.0 12.3 16.5
CE 20:4 (μΜ) 4.00 × 10−4 957 766 1056 664 564 783 1056 957 1295