Table 1.
Treatment regimens which have been repeatedly shown to be effective in eradicating H pylori
| Length of treatment (days) | Component drugs | |||
|---|---|---|---|---|
| Regimens based on clarithromycin | ||||
| 14 | Ranitidine bismuth citrate 400 mg twice daily | Clarithromycin 500 mg twice daily | ||
| 7-10 | Ranitidine bismuth citrate 400 mg twice daily | Amoxicillin 1000 mg twice daily | Clarithromycin 500 mg twice daily | |
| 7-10 | Proton pump inhibitor twice daily | Amoxicillin 1000 mg twice daily | Clarithromycin 500 mg twice daily | |
| Regimens based on metronidazole (or tinidazole) | ||||
| 14 | Bismuth compound 4 times/day | Tetracycline 500 mg 4 times/day | Metronidazole 400-500 mg 3-4 times/day | |
| 7-10 | Proton pump inhibitor twice daily | Amoxicillin 500 mg 2-3 times/day | Metronidazole 400-500 mg 2-3 times/day | |
| 4-7 | Proton pump inhibitor twice daily | Colloidal bismuth subcitrate 4 times/day | Tetracycline 500 mg 4 times/day | Metronidazole 400-500 mg 3-4 times/day |
| Regimens based on clarithromycin plus metronidazole (or tinidazole) | ||||
| 7 | Ranitidine bismuth citrate 400 mg twice daily | Clarithromycin 500 mg twice daily | Metronidazole 400-500 mg twice daily | |
| 7 | Proton pump inhibitor twice daily | Clarithromycin 500 mg twice daily | Metronidazole 400-500 mg twice daily | |