Figure 2. DMC induces the expression of promoter-methylated genes.
Real-time gene expression analysis of the p15 and CDH-1 genes in CEM cells after treatment with curcumin (Cur) 2 uM, DMC 1 uM and 5-azacytidine (5AC) 500 nM for 72 h. Data represent the average of 3 replicates ± SD and * indicates a significant difference from the corresponding control cells at p<0.05.