Table 4.

Cytotoxicity of compounds 39–41, 48–50, 58, 60, 62 and II in HT-22 and BV-2 cells.

Compound	Cytotoxicity in HT-22 Cells $({\mathbf{IC}}_{50} \overline{\mathit{x}}$ ± SEM µM)	Cytotoxicity in BV-2 Cells (${\mathbf{IC}}_{50} \overline{\mathit{x}}$ ± SEM µM)
39	8.4 ± 5.3	4.5 ± 1.9
40	19.9 ± 4.1	3.6 ± 0.7
41	>100	6.1 ± 3.1
48	36.6 ± 4.3	21.8 ± 3.8
49	>100	>100
50	>100	>100
58	67.1 ± 14.5	51.4 ± 0.8
60	9.7 ± 5.8	3.0 ± 0.0
62	58.3 ± 10.0	54.8 ± 1.9
II	>100	15.4 ± 0.6

Data expressed as the means ± SEM; N ≥ 6.