Table 3.
Secondary endpoints at 6 months follow-up for homozygous and mixed minor allele carriers.
| Homozygous Minor Allele Carriers (n = 10) % Change from Baseline (95% CI) |
Mixed Allele Carriers (n = 16) % Change from Baseline (95% CI) |
% Difference (95% CI) | p-Value | |
|---|---|---|---|---|
| Homocysteine | −48.3% (−62.3%, −34.3%) |
−18.6% (−25.6%, −11.6%) |
−29.7% (−50.7%, −8.7%) |
p < 0.01 |
| LDL-C | −11.8% (−15.8%, −7.8%) |
−4.8% (−6.8%, −2.8%) |
−7.0% (−13.0%, −1.0%) |
p < 0.01 |
| Total cholesterol | −3.2% (−5.6%, −0.8%) |
−2.1% (−4.3%, 0.1%) |
−1.1% (−5.7%, 3.5%) |
p = 0.07 |
| HDL-C | 2.8% (−0.5%, 6.1%) |
0.9% (−1.9%, 3.7%) |
1.9% (−4.2%, 8.0%) |
p = 0.12 |
| Triglycerides | −5.1% (−10.9%, 0.7%) |
−2.8% (−5.7%, 0.1%) |
−2.3% (−11.0%, 6.4%) |
p = 0.09 |
| hsCRP | −3.9% (−11.6%, 3.8%) |
−6.1% (−13.9%, 1.7%) |
2.2% (−17.7%, 13.3%) |
p = 0.22 |