FIG. 5.

Phylogenetic relationships among C2C4 sequences from the patient, the two nurses, and multiple local controls. (a) Strict consensus among 382 MP trees (tree length = 1,191). BV obtained under unweighted MP (10³ replicates) and under NJ (10⁴ replicates) are indicated above and below the branches, respectively. na, not applicable (the group was not found in the NJ bootstrap consensus tree). (b) ML phylogram (−ln L = 2662.67099) among patient, nurse 2, and a reduced set of local control sequences (i.e., redundant sequences, indicated by asterisks, were excluded from these analyses; see text for details). BV obtained under ML are indicated on the branches. Plasma viral sequences from the patient (JV32 and JV48) and nurse 2 (JV27 and JV44) were processed blind during the analyses.