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. 2024 Jun 11;16(1):2363012. doi: 10.1080/19490976.2024.2363012

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© 2024 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 1. — Categorical analysis of hierarchical clustering of methylation data CIMP status of CRC patient tumor samples.

(a) Unsupervised hierarchical clustering of 115 CRC tumor samples based on 1317 CpG sites from DREAM methylation data. b-e) Bar plots showing the patient statistics (b) sex, (c) tissue side, (d) MLH1 methylation status, and (e) CDKN2A methylation status in each CIMP status. Fisher’s exact test was used to test for statistical significance for each comparison in b-e.