Table 1.
Association between characteristics of CIMP and the Superhigh bacterial group.
| Superhigh (n = 26) | Non-Superhigh (n = 177) | p-value | |
|---|---|---|---|
| CIMP status | 0.013 | ||
| Positive | 20 (76.9%) | 92 (52.0%) | |
| Negative | 6 (23.1%) | 85 (48.0%) | |
| MLH1 methylation status* | 0.0025 | ||
| Methylated | 10 (38.5%) | 22 (12.7%) | |
| Unmethylated | 16 (61.5%) | 151 (87.3%) | |
| CDKN2A methylation status* | 0.33 | ||
| Methylated | 8 (30.8%) | 43 (24.9%) | |
| Unmethylated | 18 (69.2%) | 130 (75.1%) | |
| Sex | 0.31 | ||
| Female | 14 (53.8%) | 82 (46.3%) | |
| Male | 12 (46.2%) | 95 (53.7%) | |
| Tissue Side† | 0.066 | ||
| Distal colon | 8 (32.0%) | 86 (50.3%) | |
| Proximal colon | 17 (68.0%) | 85 (49.7%) | |
| Pathologic Stage‡ | 0.098 | ||
| Stage 1 | 2 (7.7%) | 6 (3.8%) | |
| Stage 2 | 4 (15.4%) | 29 (18.2%) | |
| Stage 3 | 13 (50.0%) | 106 (66.7%) | |
| Stage 4 | 7 (26.9%) | 18 (11.3%) | |
| Age | 0.066 | ||
| Over 70 | 14 (53.8%) | 64 (36.2%) | |
| Under 70 | 12 (46.2%) | 113 (63.8%) |
*.missing 4 data points.
†.missing 7 data points.
‡.missing 18 data points.
Fisher’s exact test for all characteristics.
Bold denotes the significance