Figure 3.

Diet supplementation with a lipid extract of H. elongata prevents cognitive decline in APPswePS1ΔE9 mice. The cognitive performance of WT and APPswePS1ΔE9 mice that received H. elongata extract or S. fusiforme SCF extract was determined with an object recognition task (ORT) (a), object location task (OLT) (b), and Y-maze spontaneous alternation test (c). Data are represented as mean ± SEM (n = 8–14 per group) and were analyzed with a one-sample t-test. D2 values relative to 0: * p < 0.05, *** p < 0.001, ns: p ≥ 0.05.