Fig 3. Translational proportions for all therapies with ≥10 years development time since the first published animal study.

Proportions of translation from animals to any clinical study (green), to an RCT (yellow), or to (FDA) approval (red) overall (A), for circulatory system diseases (B), for neurological diseases (C), for mental health disorders (D), for musculoskeletal diseases (E), and for cancer (F). The data underlying this figure can be found on https://osf.io/frjm4 (Sheet: Translation). The code underlying this figure can be found in S1 Code (https://osf.io/9fgru). RCT, randomized controlled trial.