Table 3. Distribution of studies concerning HPV in lesions of the conjunctiva, published between 1986 and 1994, according to the first author, the histopathologic diagnosis of the lesions, the frequency and type of HPV found and the technique employed.
Reference | HPV type | frequency | diagnosis | technique |
---|---|---|---|---|
Naghashfar,8 1986. | 6 | 1/1 | papilloma | SB / ISH |
McDonnell,6 1986. | 16 | 15/23 | papilloma | ISH |
0/28 | dysplasia/ca | ISH | ||
McDonnell,9 1989. | 16 | 12/16 | dysplasia/ca | PCR |
Lauer,10 1990. | 16,18 | 4/5 | dysplasia/ca | PCR |
Odrich,11 1991. | 16 | 3/3 | dysplasia/ca | |
McDonnell,3 1992. | 16 | 35/42 | dysplasia/ca | PCR |
37/42 | ||||
Mincione,12 1992. | 6,11 | 2/4 | papilloma | ISH |
Tuppurainen,13 1992. | 6,11,16,18 | 0/4 | carcinoma | PCR / ISH |
Cha,15 1994. | 16 | 21/31 | dysplasia/ca | PCR |
18 | 2/31 |
Legend: SB = Southern blot; ISH = in situ hybridization; PCR = polymerase chain reaction.