Table 2.

Forward MR sensitivity analysis.

		Inverse variance weighted		MR-Egger
Panel	Immune traits	Q	P	Intercept	P
cDC	CD62L− monocyte %monocyte	17.81	0.600	0.005	0.850
Treg	Secreting Treg % CD4 Treg	32.24	0.265	0.009	0.575
Treg	CD28−DN (CD4−CD8−) % DN	28.29	0.344	0.015	0.404
B cell	CD28 on CD28+DN (CD4−CD8−)	0.33	0.847	−0.055	0.765
B cell	IgD on IgD+CD38dim	20.34	0.500	0.008	0.655
B cell	CD40 on CD14−CD16+monocyte	31.29	0.179	−0.008	0.705
B cell	CCR2 on monocyte	20.29	0.624	−0.019	0.303
TBNK	CD45 on HLADR+CD8br	4.71	0.997	0.009	0.592
cDC	CD11c+CD62L−monocyte AC	13.54	0.889	−0.006	0.019
Treg	Resting Treg%CD4 Treg	25.49	0.601	-0.038	0.062
Treg	Activated & resting Treg%CD4 Treg	29.27	0.253	−0.006	0.749
Treg	CD28+DN (CD4−CD8−)%DN	28.29	0.344	−0.015	0.404
Treg	CD45RA−CD28−CD8br%T cell	180.63	0.311	0.0005	0.964
Treg	CD45RA+CD28−CD8br AC	733.87	0.131	−0.009	0.167
Treg	CD28 on secreting Treg	15.73	0.330	−0.019	0.352
Treg	CD28 on activated & secreting Treg	19.45	0.617	−0.001	0.936
B cell	CD19 on IgD+CD38−	30.79	0.375	0.021	0.195
B cell	CD19 on IgD+CD38−naïve	17.57	0.484	−0.010	0.508
B cell	CD20 on IgD+CD38−	20.67	0.658	−0.033	0.061
B cell	CD20 on IgD−CD24−	11.80	0.988	−0.012	0.450
B cell	CD20 on IgD−CD27−	16.26	0.505	0.028	0.355
Maturation stages of T cell	CM DN (CD4−CD8−) AC	0.176	0.981	0.025	0.741
Maturation stages of T cell	HVEM on CM CD4+	14.58	0.482	0.019	0.401
Maturation stages of T cell	HVEM on CD8br	23.59	0.051	-0.010	0.814
Monocyte	CX3CR1 on monocyte	32.34	0.148	0.021	0.477
TBNK	T cell %lymphocyte	19.20	0.258	0.029	0.527

MR, Mendelian randomization.