Table 2.
Overview of comparison between ChEIs and placebo for Alzheimer disease regarding to adverse events.
| Pooled results from FEM | |||
|---|---|---|---|
| Adverse events | Sample size | OR | 95% CI |
| AEs from any cause | 7819 | 1.38 | 1.25–1.53 |
| Discontinued due to AEs | 6202 | 1.47 | 1.21–1.80 |
| Severe AEs | 3720 | 1.25 | 0.86–1.81 |
| Serious AEs (fatal or nonfatal) | 7064 | 1.00 | 0.83–1.20 |
| Any related AEs | 3369 | 1.60 | 1.35–1.89 |
| Deaths | 4502 | 0.91 | 0.52–1.58 |
AEs, adverse events; FEM, fixed-effect model; OR, odds ratio.
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