Table 1.
Relationships among NLR, SII, PLR, LMR, PNI and clinicopathological characteristics in patients with esophageal carcinoma.
| Variables | Total patients | NLR | SII | PLR | LMR | PNI | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Low (176) |
High (70) |
P | Low (184) |
High (62) |
P | Low (89) |
High (157) |
P | Low (167) |
High (79) |
P | Low (65) |
High (181) |
P | |||
| Age (years, %) | 65.5 ± 7.4 | 65.1 ± 7.3 | 66.4 ± 7.6 | .220 | 65.2 ± 7.3 | 66.2 ± 7.7 | .383 | 65.4 ± 7.2 | 65.5 ± 7.5 | .929 | 65.5 ± 7.5 | 65.3 ± 7.1 | .849 | 66.9 ± 6.5 | 65.0 | .072 | |
| Gender | |||||||||||||||||
| Male | 181 | 127 | 54 | .424 | 132 | 49 | .260 | 66 | 115 | .877 | 137 | 44 | <.001 | 47 | 134 | .787 | |
| Female | 65 | 49 | 16 | 53 | 12 | 23 | 42 | 32 | 33 | 18 | 47 | ||||||
| Smoking | |||||||||||||||||
| No | 128 | 86 | 41 | .169 | 94 | 34 | .558 | 39 | 88 | .065 | 74 | 53 | .001 | 34 | 93 | .898 | |
| Yes | 119 | 90 | 29 | 91 | 28 | 50 | 69 | 93 | 26 | 31 | 88 | ||||||
| Alcohol drinking | |||||||||||||||||
| No | 122 | 87 | 35 | .936 | 92 | 30 | .826 | 41 | 81 | .405 | 70 | 52 | <.001 | 29 | 93 | .349 | |
| Yes | 124 | 89 | 35 | 92 | 32 | 48 | 76 | 97 | 27 | 36 | 88 | ||||||
| Differentiation | |||||||||||||||||
| Low | 20 | 10 | 10 | .061 | 11 | 9 | .104 | 4 | 16 | .043 | 16 | 4 | .423 | 4 | 16 | .545 | |
| Medium | 205 | 149 | 56 | 157 | 48 | 73 | 132 | 138 | 67 | 57 | 148 | ||||||
| High | 21 | 17 | 4 | 16 | 5 | 12 | 9 | 13 | 8 | 4 | 17 | ||||||
| Vascular involvement | |||||||||||||||||
| Negative | 212 | 155 | 57 | .173 | 162 | 50 | .144 | 77 | 135 | .908 | 141 | 71 | .248 | 52 | 160 | .092 | |
| Positive | 34 | 21 | 13 | 22 | 12 | 12 | 22 | 26 | 8 | 13 | 21 | ||||||
| Nerve involvement | |||||||||||||||||
| Negative | 213 | 152 | 61 | .871 | 157 | 56 | .318 | 72 | 141 | .049 | 144 | 69 | .811 | 60 | 153 | .115 | |
| Positive | 33 | 24 | 9 | 27 | 6 | 17 | 16 | 23 | 10 | 5 | 28 | ||||||
| Length (mm, %) | 4.2 ± 1.3 | 4.0 ± 1.1 | 4.9 ± 1.5 | <.001 | 4.0 ± 1.2 | 4.8 ± 1.4 | <.001 | 4.0 ± 1.2 | 4.4 ± 1.3 | .029 | 4.3 ± 1.3 | 4.0 ± 1.2 | .082 | 4.5 ± 1.3 | 4.1 ± 1.2 | .051 | |
| Postoperative treatment | |||||||||||||||||
| None | 151 | 107 | 44 | .565 | 117 | 34 | .622 | 58 | 93 | .817 | 99 | 52 | .817 | 46 | 105 | .112 | |
| Radiotherapy | 17 | 12 | 5 | 12 | 5 | 5 | 12 | 13 | 4 | 3 | 14 | ||||||
| Chemotherapy | 54 | 42 | 12 | 39 | 15 | 18 | 36 | 38 | 16 | 14 | 40 | ||||||
| Chemoradiotherapy | 24 | 15 | 9 | 16 | 8 | 8 | 16 | 18 | 6 | 2 | 22 | ||||||
LMR = lymphocyte-to-monocyte ratio, NLR = neutrophil-to-lymphocyte ratio, PLR = platelet-to-lymphocyte ratio, PNI = prognostic nutritional index, SII = systemic immune-inflammation index.