Table 2.
Prognostic factors for OS in patients with postoperative staged T3N0M0 esophageal carcinoma.
| Univariate analysis | Multivariate analysisa | |||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Gender | ||||
| Male | 1 | .731 | ||
| Female | 1.08 (0.71,1.63) | |||
| Smoking | ||||
| No | 1 | .559 | ||
| Yes | 1.12 (0.77,1.62) | |||
| Alcohol drinking | ||||
| No | 1 | .268 | ||
| Yes | 1.23 (0.85,1.79) | |||
| Differentiation | ||||
| Low | 1 | .005 | 1 | .006 |
| Medium | 0.48 (0.27,0.85) | .011 | 0.54 (0.27,0.98) | .043 |
| High | 0.21 (0.074,0.57) | .002 | 0.19 (0.07,0.54) | .002 |
| Vessel involvement | ||||
| Negative | 1 | .046 | 1 | .053 |
| Positive | 1.64 (1.01,2.66) | 1.66 (0.99–2.76) | ||
| Nerve involvement | ||||
| Negative | 1 | .977 | 1 | .637 |
| Positive | 0.98 (0.58,1.71) | 1.16 (0.64–2.10) | ||
| Postoperative treatment | ||||
| None | 1 | .014 | 1 | .003 |
| Radiotherapy | 0.88 (0.47,1.83) | .735 | 0.79 (0.36–1.57) | .455 |
| Chemotherapy | 0.56 (0.34,0.92) | .021 | 0.48 (0.29–0.81) | .005 |
| Chemoradiotherapy | 0.31 (0.13,0.77) | .012 | 0.26 (0.10–0.66) | .004 |
| NLR | ||||
| Low | 1 | <.001 | 1 | .116 |
| High | 2.35 (1.61,3.43) | 1.50 (0.91–2.48) | ||
| SII | ||||
| Low | 1 | <.001 | 1 | .039 |
| High | 2.23 (1.51,3.30) | 1.76 (1.03–3.01) | ||
| PLR | ||||
| Low | 1 | .044 | 1 | .850 |
| High | 1.51 (1.01.2.26) | 0.85 (0.52–1.39) | ||
| LMR | ||||
| Low | 1 | .002 | 1 | .072 |
| High | 0.52 (0.33,0.81) | 0.64 (0.40–1.04) | ||
| PNI | ||||
| Low | 1 | <.001 | 1 | .037 |
| High | 0.44 (0.30,0.65) | 0.62 (0.40–0.97) | ||
CI = confidence interval, HR = hazard ratio, LMR = lymphocyte-to-monocyte ratio, NLR = neutrophil-to-lymphocyte ratio, PLR = platelet-to-lymphocyte ratio, PNI = prognostic nutritional index, SII = systemic immune-inflammation index.
a
Adjusted for age, gender, smoking, alcohol drinking.