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. 2024 May 22;56(6):1278–1287. doi: 10.1038/s41588-024-01769-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — a, Number and proportion of genes impacted by at least one eQTL for accessory genes (inner ring), core genes (middle ring) and the combined set (outer ring). Fold enrichment for core and accessory genes on the proportion of genes impacted compared with the combined set are presented as bars (OR). Significant enrichment based on a two-sided Fisher’s test is indicated by the three asterisks (OR = 1.33, two-sided Fisher’s test, P = 0.0002676). b, Comparison of the absolute effect size for eQTLs associated with accessory or core gene expression traits. P values were determined using a two-sided Wilcoxon rank-sum test. Sample sizes are shown in the plots. The center of the box plots corresponds to the median; the upper and lower bounds correspond to the third and first quartiles. The whiskers correspond to the upper and lower bounds 1.5× the IQR. n = 3,378 for associations with accessory genes and n = 6,092 for associations with core genes (see also Supplementary Fig. 11).