Table 3.
Treatment-emergent adverse events
| Grade 1–2 | Grade 3 | Grade 4 | |
|---|---|---|---|
| Diarrhea | 8 (53%) | 5 (33%) | 1 (6.7%) |
| leukopenia | 8 (53%) | 1 (6.7%) | 0 |
| Vomiting | 7 (47%) | 0 | 0 |
| Anemia | 6 (40%) | 0 | 0 |
| Nausea | 4 (27%) | 0 | 0 |
| Fatigue | 3 (20%) | 0 | 0 |
| Rash | 3 (20%) | 0 | 0 |
| Neutropenia | 3 (20%) | 0 | 0 |
| Anorexia | 3 (20%) | 0 | 0 |
| Oral ulcer | 2 (13%) | 0 | 0 |
| Dizziness | 2 (13%) | 0 | 0 |
| Marrow suppression | 2 (13%) | 1 (6.7%) | 0 |
| Abdominal distension | 1 (6.7%) | 0 | 0 |
| Headache | 1 (6.7%) | 0 | 0 |
Data are n (%). Grade 1–2 events occur in all patients and all grade 3 and 4 events are reported. Each patient was counted once for the highest grade of each event experienced.