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. 2024 Jun 13;15:5025. doi: 10.1038/s41467-024-49117-z

Fig. 8. Pre-existing H1N1pdm09 immunity reduces swine α-H1N2 influenza virus clinical signs.

Fig. 8

A The symptoms for each intranasally α-swH1N2-infected ferret from Figs. 5 and 6 having either no prior immunity (N = 22), H1N1pdm09-imm (N = 6) or H3N2-imm (N = 4) were added together to assign each animal a cumulative score. Each dot represents the cumulative symptoms score for a single ferret. Two-way ANOVA analysis was used to determine statistically significant differences (*p = 0.0452). B The symptoms for each airborne α-swH1N2-infected ferret from Figs. 5 and 6 having either no prior immunity (N = 7), H1N1pdm09-imm (N = 10) or H3N2-imm (N = 4) were added together to assign each animal a cumulative score. Each dot represents the cumulative symptoms score for a single ferret. C Percent number of intranasally infected ferrets from panel A displaying each symptom on the indicated days post-infection. D Percent number of recipient ferrets from B displaying each symptom on the indicated days post-exposure. For C and D, wt = weight.