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. 2024 May 31;12:1416697. doi: 10.3389/fcell.2024.1416697

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Copyright © 2024 Ponce, Luck and Okimoto.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Anatomical Localization of CIC-rearranged Primary Tumors. Primary tumor location of CIC-fusion positive cases reported in the literature. CIC::DUX4 (red circles) tumors localized primarily in the soft tissue. CIC::NUTM1 (green triangles) tumors were predominantly observed in the central nervous system. CIC::LEUTX (purple squares) tumors were confined mostly in the brain, while CIC::FOXO4 (blue diamonds) tumors were interspersed in the scalp, neck, and thigh. Original unlabeled anatomical image from Vecton/Shutterstock.com.