Table 5.

Reverse causal association between PPP and cytokines.

Cytokines (outcome)	MR method	No. SNP	OR	95%CI	p-value
CCL19	IVW	9	0.98	0.82–1.16	0.780
	Weighted median		0.97	0.70–1.36	0.884
	MR-Egger		0.91	0.59–1.41	0.694
CXCL6	IVW	9	1.01	0.76–1.32	0.989
	Weighted median		1.20	0.93–1.52	0.16
	MR-Egger		1.22	0.60–2.48	0.60
IL-6	IVW	35	0.96	0.92–1.01	0.113
	Weighted median		0.95	0.84–1.07	0.374
	MR-Egger		0.93	0.84–1.03	0.187

SNPs, single-nucleotide polymorphism; IVW, inverse-variance weighted; MR. Mendelian randomization.