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. 2024 May 31;15:1403694. doi: 10.3389/fmicb.2024.1403694

Table 2.

The most upregulated genes in the ΔccpC strain compared to the levels in the wildtype F2365 strain.

Gene id Gene description log2Fold change p value
DNA repair
LMOf2365_1500 DNA polymerase III, delta subunit 1.4 6.9E-03
LMOf2365_1596 Bacterial DNA polymerase III alpha subunit (dnaE) 1.7 3.0E-03
LMOf2365_0177 DNA polymerase III subunit, delta subunit (holB) 1.9 3.0E-03
LMOf2365_1587 DNA polymerase I: 5′-3′ exonuclease, C-terminal SAM fold (polA) 1.4 6.7E-03
LMOf2365_1417 Protein RecA bacterial DNA recombination protein (recA) 2.0 7.9E-04
LMOf2365_0005 DNA replication and repair protein: RecF/RecN/SMC N terminal (recF) 1.6 1.4E-02
LMOf2365_1479 DNA repair protein: Recombination protein O N terminal (recO) 1.9 2.0E-02
LMOf2365_2682 Recombination protein: Toprim domain (recR) 1.8 1.9E-02
LMOf2365_1920 Holliday junction resolvase: Recombination protein U (recU) 2.0 5.8E-03
LMOf2365_1552 Holliday junction ATP-dependent DNA helicase: HHH domain (ruvA) 1.2 1.3E-02
LMOf2365_1551 Holliday junction ATP-dependent DNA helicase: N-terminus (ruvB) 1.3 1.0E-02
LMOf2365_1320 LexA repressor: Peptidase S24-like (lexA) 2.0 3.0E-03
LMOf2365_0001 Chromosomal replication initiator protein (dnaA) 1.7 4.9E-03
LMOf2365_1924 Replication and repair (dnaD) 0.9 4.8E-02
LMOf2365_1586 Formamidopyrimidine-DNA glycosylase HTH domain (mutM) 1.5 2.5E-03
LMOf2365_1422 DNA mismatch repair protein: MutS domain V (mutS-2) 1.1 1.3E-02
Iron, zinc and manganese metabolism (PerP system)
LMOf2365_1466 Zinc ABC transporter ATP-binding protein ZurA (zurA-2) 1.5 3.0E-03
LMOf2365_1464 Transcriptional regulator ZurR (zurR) 1.8 2.0E-03
LMOf2365_1707 Peroxide-responsive transcriptional repressor (PerR) (PerR) 1.7 7.2E-03
LMOf2365_1986 Ferric uptake regulator family (fuR) 1.9 2.2E-03
LMOf2365_1907 Transcriptional regulator MntR: Iron dependent repressor 1.7 9.0E-03
Protein export
LMOf2365_1872 Lipoprotein signal peptidase: Signal peptidase (SPase) II (lspA) 2.0 1.0E-02
LMOf2365_0257 Protein translocase subunit (secE) 2.1 4.2E-03
LMOf2365_2424 Probable protein-export membrane protein (secG) 2.2 1.5E-03
LMOf2365_1287 Signal peptidase IB: Peptidase S24-like (sipX) 1.9 2.3E-03
LMOf2365_1288 Signal peptidase I: Peptidase S24-like 1.5 1.7E-02
LMOf2365_1289 Signal peptidase I: Peptidase S24-like 1.6 2.8E-03
Peptidoglycan biosynthesis
LMOf2365_2499 UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) (murA-)1 1.5 1.1E-02
LMOf2365_1439 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain (murB) 1.9 9.0E-04
LMOf2365_1483 Undecaprenol kinas: Prokaryotic diacylglycerol kinase (dgkA) 1.5 4.6E-03
LMOf2365_2069 Phospho-N-acetylmuramoyl-pentapeptide-transferase: Glycosyl transferase family 4 (mraY) 1.6 1.1E-02
LMOf2365_1332 Isoprenyl transferase: Putative undecaprenyl diphosphate synthase (uppS) 1.8 1.2E-02
LMOf2365_0872 D-alanine--D-alanine ligase: C-terminus 1.5 1.5E-02
LMOf2365_2399 Peptidoglycan glycosyltransferase: Cell cycle protein 2.1 1.3E-03
Teichoic acid biosynthesis
LMOf2365_2526 Alpha-galactosylglucosyldiacylglycerol synthase 1.4 2.8E-03
LMOf2365_2527 Alpha-monoglucosyldiacylglycerol synthase: Glycosyl transferases group 1 1.5 1.3E-02
LMOf2365_2491 Uncharacterized Cell envelope-related transcriptional attenuator 1.8 4.2E-03
LMOf2365_1097 Teichoic acid poly(ribitol-phosphate) polymerase: Poly(glycerophosphate) glycerophosphotransferase 1.5 1.0E-02
LMOf2365_0979 Probable undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase: Glycosyl transferase family 4 1.6 1.8E-02