Table 4.
KEGG pathway enrichment analysis for upregulated and downregulated genes in ΔccpC strain compared to the levels in the wildtype F2365 strain.
| Description | p value | Corrected p value | Gene no. |
|---|---|---|---|
| Upregulated pathway | |||
| Homologous recombination | 5.72E-05 | 2.08E-03 | 23 |
| Terpenoid backbone biosynthesis | 6.60E-05 | 2.08E-03 | 10 |
| Protein export | 5.49E-04 | 8.65E-03 | 8 |
| Teichoic acid biosynthesis | 1.81E-03 | 2.28E-02 | 9 |
| Peptidoglycan biosynthesis | 5.47E-03 | 5.74E-02 | 8 |
| Nucleotide metabolism | 9.63E-02 | 6.74E-01 | 10 |
| Glycerophospholipid metabolism | 1.19E-01 | 7.48E-01 | 5 |
| Two-component system | 1.35E-01 | 7.62E-01 | 13 |
| Bacterial secretion system | 1.76E-01 | 7.92E-01 | 4 |
| Downregulated pathway | |||
| Phosphotransferase system (PTS) | 2.55E-06 | 1.43E-04 | 28 |
| Valine, leucine and isoleucine biosynthesis (branched chain amino acids) | 3.17E-05 | 8.89E-04 | 8 |
| Fructose and mannose metabolism | 1.49E-03 | 2.78E-02 | 15 |
| Starch and sucrose metabolism | 1.13E-02 | 1.58E-01 | 16 |
| Inositol phosphate metabolism | 1.78E-02 | 1.87E-01 | 5 |
| Biosynthesis of amino acids | 2.00E-02 | 1.87E-01 | 30 |
| Porphyrin metabolism | 3.38E-02 | 2.70E-01 | 10 |
| 2-oxocarboxylic acid metabolism | 4.19E-02 | 2.93E-01 | 7 |