Figure 7.

SMTNL1 facilitates glucose uptake and glycogen storage of Ishikawa cells. Glycogen content of control/P4/GDB treated Ishikawa cells were normalized to protein concentration. Control MOCK group value was taken as 100% and all other all other values were compared to that and expressed as ratio. Data are displayed as bar charts, values represent n=3-9 mean +/- SD. Groups were compared by two-tailed t-test. Bars represent n=3, mean +/- SD. p< 0.05 (*), p<0.01 (**), p<0.001 (***) and p<0.0001 (****) (A). 2-NDBG glucose uptake of Ishikawa cells were assessed in control, progesterone (P4), and gestational diabetes (GDB) conditions with or without SMTNL1 overexpression. Values were normalized and expressed as the ratio of the control MOCK group, which was considered 100%. Bars represent n=3, mean +/- SD. Two groups were compared by unpaired two-tailed t-test, and four groups or more were compared by two-way ANOVA, where: p< 0.05 (*) and p<0.01 (**) (B).