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. 2024 Jan 6;11(5):101207. doi: 10.1016/j.gendis.2024.101207

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© 2024 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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figs5 — Elevation of immune-related genes in PMC and GMC indicates survival rate of gastric cancer. (A) Dot plot showing the top 7 enriched and 3 key GO Biological Process or pathways with p value<0.05 in PMC. (B) Volcano plot showing the up-regulated and down-regulated genes in GMC. Significant differential expressed genes (DEGs) are defined as log fold change ≥1 or ≤-1 and adjusted p value<0.05 using Wilcoxon rank-sum test. (C) Venn diagram showing the overlap of up-regulated and down-regulated DEGs between GMC and PMC. (D) Dot plot showing the top 10 enriched GO Biological Process or pathways with p value<0.05 in GMC. (E) Heatmap shows the expression profile of immune-related genes in the enriched pathways such as “antigen processing and presentation of peptide”, “humoral immune response” and “granulocyte migration” et al.. (F) Immune-related genes with a distinct expression pattern in PMC and GMC in H. pylori infected compared with non-infected group.