figs7.

Cell-cell communications aberrations in IM patient with H. pylori infection. (A) Inferred interactions and interaction strength in H. pylori positive group compared with H. pylori negative group. (B) Complex heatmap shows the count (the left panel) and strength (the right panel) of cell-cell interaction among different cell types in H. pylori infected and non-infected group; a red block means a higher cell-cell interaction frequency or strength in H. pylori infected compared with non-infected group, and vice versa . (C) Signaling patterns analysis shows relative information flow strength of signaling pathways mediated interactions within two groups. (D) The outgoing signaling patterns of each cell in H. pylori infected and non-infected groups. (E) Dot plot shows the up-regulated signals among PMC, GMC, PC, macrophage, fibroblasts and T cell in H. pylori infected group.