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H. pylori infection promotes gastric cancerization through TFs regulatory network. (A) Heatmap shows the Regulon Specificity Score (RSS) of single-cell subtype-specific TFs in each cell type. (B) Feature plot shows the distribution of PMC in all cells and regulon-activity of FOXO1 in H. pylori infected compared with non-infected group. (C) Motif enrichment analysis of FOX family in proximal regions of DEGs in PMC using MEME suite.
