Fig. 5.

Proteomics of pericyte-specific secreted proteins in response to hypoxia.A, volcano plot showing the differentially expressed proteins between HM compared to NM (left panel) and the significantly regulated signaling pathways from the GSEA hallmark database (right panel), after 24 h of hypoxia, n = 3. B, volcano plot showing the differentially expressed proteins between HS compared to NS (left panel) and the significantly regulated signaling pathways from the GSEA hallmark database (right panel), after 24 h of hypoxia, n = 3. EMT, epithelial mesenchymal transition; HM, hypoxia–monoculture; HS, hypoxia–spheroids; NM, normoxia–monoculture; NS, normoxia–spheroids.