Table 10.
Exclusion Criteria Applied for UKBB IBS Cases and Control Subjects
| Data-field | Trait | |
|---|---|---|
| ICD10 | 41202 and 41204 | K50 (Crohn's disease) |
| K51 (Ulcerative colitis) | ||
| K52 (Other and unspecified noninfective gastroenteritis and colitis) | ||
| K86 (Other diseases of pancreas) | ||
| K90 (Intestinal malabsorption) | ||
| K550 (Acute vascular disorders of intestine) | ||
| K551 (Chronic vascular disorders of intestine) | ||
| K627 (Radiation proctitis) | ||
| C15 (Malignant neoplasm of esophagus) | ||
| C16 (Malignant neoplasm of stomach) | ||
| C17 (Malignant neoplasm of small intestine) | ||
| C18 (Malignant neoplasm of colon) | ||
| C19 (Malignant neoplasm of rectosigmoid junction) | ||
| C20 (Malignant neoplasm of rectum) | ||
| C21 (Malignant neoplasm of anus and anal canal) | ||
| C22 (Malignant neoplasm of liver and intrahepatic bile ducts) | ||
| C23 (Malignant neoplasm of gallbladder) | ||
| C24 (Malignant neoplasm of other and unspecified parts of biliary tract) | ||
| C25 (Malignant neoplasm of pancreas) | ||
| C26 (Malignant neoplasm of other and ill-defined digestive organs) | ||
| K57 (Diverticular disease of intestine) | ||
| K58 (Irritable bowel syndrome)a | ||
| Self-report | 20002 | 1462 (Crohn’s disease) |
| 1463 (Ulcerative colitis) | ||
| 1459 (Colitis / not Crohn’s or ulcerative colitis) | ||
| 1461 (Inflammatory bowel disease) | ||
| 1164 (Pancreatic disease) | ||
| 1165 (Pancreatitis) | ||
| 1456 (Malabsorption/coeliac disease) | ||
| 1191 (Gastrointestinal bleeding) | ||
| 1509 (Gastroenteritis/dysentery) | ||
| 1600 (Bowel / intestinal perforation) | ||
| 1601 (Bowel / intestinal infarction) | ||
| 1602 (Bowel / intestinal obstruction) | ||
| 1135 (Stomach disorder) | ||
| 1458 (Diverticular disease / diverticulitis) | ||
| 1562 (Food intolerance) | ||
| 1154 (Irritable bowel syndrome)a | ||
| DHQ | 21068 | Positive answer for "have you been diagnosed with coeliac disease/gluten sensitivity?" |
| 21024 | Positive answer for "have you ever been diagnosed with IBS?" | |
| 21025 | Different answer than 'never' for "in the last 3 months, how often did you have discomfort or pain anywhere in your abdomen?"a | |
| 21025–21034 | Fulfilling Rome III criteria for irritable bowel syndromea | |
DHQ, Digestive Health Questionnaire; IBS, irritable bowel syndrome; ICD10, International Classification of Diseases,10th Edition; UKBB, UK Biobank.
a
Exclusion criterion applied to control subjects only.