Figure 3.

Morphology and origin of SiCry-15X cell line. (A) Microscopic image of SiCry-15X (scale bar, 100 µm). The cells adhered and grew as monolayers. (B) Amplification of human and mouse mtDNA. SCC VII, a mouse-derived cell line, and MKN74, a human-derived cell line, were used as positive controls, and purified water was used as the NC. 18S rRNA was used as the internal control. In PDXs, both human and mouse components were combined, whereas SiCry-15X cells consisted only of human components. NC, negative control; rRNA, ribosomal RNA; PDX, patient-derived xenograft.