Table 1.

Trend analysis of the KD incidence from 2001 to 2020

Age	All subjects				Male				Female
(year)	AAPC(%)	95% CI	p value		AAPC(%)	95% CI	p value		AAPC(%)	95% CI	p value
< 1	2.8	(2.1 to 3.5)	< 0.001		2.6	(1.8 to 3.3)	< 0.001		3.3	(2.4 to 4.2)	< 0.001
1	4.7	(3.9 to 5.5)	< 0.001		4.2	(3.4 to 5.0)	< 0.001		5.5	(4.2 to 6.7)	< 0.001
2	3.7	(2.7 to 4.6)	< 0.001		3.2	(2.1 to 4.3)	< 0.001		4.4	(3.2 to 5.7)	< 0.001
3	3.5	(2.5 to 4.5)	< 0.001		3.0	(1.6 to 4.5)	< 0.001		4.2	(2.6 to 6.0)	< 0.001
4	4.9	(3.3 to 6.5)	< 0.001		4.3	(2.7 to 6.0)	< 0.001		5.8	(3.7 to 7.9)	< 0.001
5	4.2	(2.6 to 5.8)	< 0.001		4.3	(2.2 to 6.5)	< 0.001		3.9	(1.4 to 6.5)	0.002
6–17	4.7	(2.9 to 6.5)	< 0.001		5.7	(3.4 to 8.1)	< 0.001		3.5	(0.5 to 6.6)	0.023
0–5	4.2	(3.5 to 4.9)	< 0.001		3.8	(3.1 to 4.5)	< 0.001		4.9	(4.1 to 5.7)	< 0.001
0–17	5.4	(4.6 to 6.3)	< 0.001		4.9	(4.0 to 5.7)	< 0.001		6.2	(5.1 to 7.2)	< 0.001

AAPC: average annual percent change. CI: confidence interval