Table 2.
MR results related to DVT and thyroid diseases
| Methods | No. of SNPs | MR analysis results | Heterogeneity | Pleiotropy | |||||
|---|---|---|---|---|---|---|---|---|---|
| OR | p | Cochran’s Q | p | MR-Egger intercept | p | MR-PRESSO Global Test | p | ||
| Autoimmune hyperthyroidism on DVT | |||||||||
| IVW | 5 | 1.0009 | 0.024 | 0.649 | 0.958 | – | – | 0.919 | 0.972 |
| MR-Egger | 5 | 1.001 | 0.385 | 0.629 | 0.890 | − 0.00008 | 0.896 | ||
| Weighted median | 5 | 1.001 | 0.028 | – | – | – | – | ||
| Subacute thyroiditis on DVT | |||||||||
| IVW | 3 | 1.00009 | 0.833 | 3.047 | 0.218 | – | – | Not enough instrumental variables | Not enough instrumental variables |
| MR-Egger | 3 | 0.999 | 0.480 | 0.983 | 0.321 | 0.0007 | 0.387 | ||
| Weighted median | 3 | 0.999 | 0.674 | – | – | – | – | ||
| Hypothyroidism on DVT | |||||||||
| IVW | 26 | 1.001 | 0.123 | 38.433 | 0.042 | – | – | 44.027 | 0.020 |
| MR-Egger | 26 | 1.005 | 0.013 | 31.943 | 0.128 | − 0.0005 | 0.037 | ||
| Weighted median | 26 | 1.001 | 0.162 | – | – | – | – | ||
| Malignant neoplasm of thyroid gland on DVT | |||||||||
| IVW | 3 | 0.999 | 0.849 | 0.249 | 0.883 | – | – | Not enough instrumental variables | Not enough instrumental variables |
| MR-Egger | 3 | 1.001 | 0.728 | 0.002 | 0.964 | − 0.0006 | 0.707 | ||
| Weighted median | 3 | 0.999 | 0.802 | – | – | – | – | ||