Table 12.

List of dysregulated miRNA to aging in human body fluids.

Sample	miRNA	Expression	Method	References
Serum	miR-222, miR-92a, miR-375	Upregulated	Solexa sequencing, RT-qPCR	Zhang et al. (2015)	miR-142-5p, miR-130b, miR-29b, miR-340	Downregulated	Solexa sequencing, RT-qPCR	Eschenhagen and Zimmermann (2005) and Catanesi et al. (2020)	miR-181a-5p, miR-151a-3p, miR-1248.	Downregulated	Illumina sequencing, RT-qPCR	Hooten et al. (2013)	miR-20a	Downregulated	RT-qPCR	Sawada et al. (2014)	miR-1225-3p, miR-211-5p, miR-5095	Upregulated	RT-qPCR	Smith-Vikos and Slack (2012)	miR-340, miR-374a-5p, miR-376c-3p	Downregulated	RT-qPCR	Gerasymchuk et al. (2020) and Eshkoor et al. (2022)
Plasma	miR-142-3p, miR-126-3p, let-7a-5p, miR-30b-5p, miR-30c-5p, miR-210	Upregulated	RT-qPCR	Ameling et al. (2015)	miR-93-5p	Downregulated	RT-qPCR		miR-126-3p	Upregulated	RT-qPCR	Olivieri et al. (2014)	miR-619, miR-3615	Downregulated	Illumina sequencing	Wu S. et al. (2016)
Saliva	miR-24-3p	Upregulated	Microarray, RT-qPCR	Machida et al. (2015)
Whole blood	miR-1284, miR-1262, miR-145-5p, miR-93-3p, miR-34a-5p	Upregulated	Microarray and Illumina sequencing	Meder et al. (2014)