Table 5.

List of reported miRNAs in multiple sclerosis.

Source	MiRNA	Expression	Method	References
Serum	miR-223, miR148b, miR-24, miR-34b, miR-324-3p	Upregulated	TaqMan low-density arrays	Vallelunga et al. (2014)
	miR-15b, miR-23a, miR-223	Downregulated	TaqMan, RT-qPCR	Fenoglio et al. (2013)
	miR-572	Downregulated	RT-qPCR	Mancuso et al. (2015)
	miR-339-5p	Downregulated	TaqMan low-density arrays,	Vallelunga et al. (2014)
	miR-15a-3p, miR-34c-5p	Downregulated	Microarray, RT-qPCR	Perdaens et al. (2020)
Plasma	miR-1826, miR-614, miR-422a, miR-572, miR-648, miR-22	Upregulated	Microarray Analysis	Siegel et al. (2012)
	let-7d, miR-140-3p, miR-22, miR-30e, miR-574-3p, miR-210, miR-92a-1, miR-145, miR-500	Upregulated	RT-qPCR	Gandhi et al. (2013)
	miR-155	Upregulated	RT-qPCR	Thamilarasan et al. (2012)
	miR-1979	Downregulated	Microarray, RT-qPCR	Siegel et al. (2012)
Blood	miR-18b, miR-599, miR-96	Upregulated	RT-qPCR	Otaegui et al. (2009)
	miR-223, miR-145, miR-584, miR-491-5p, miR-186, miR-664, miR-422a, miR-1275, miR-142-3p	Upregulated	Microarray	Keller et al. (2009)
	miR-16-2-3p	Upregulated	NGS, microarray analysis, RT-qPCR	Keller et al. (2014)
	miR-150-5p, miR-155-5p	Upregulated	Microarray, RT-qPCR	Perdaens et al. (2020)
	miR-7-1-3p, miR-20a-5p	Downregulated	NGS, microarray analysis, RT-qPCR	Keller et al. (2014)
	miR-15a-3p, miR-34c-5p	Downregulated	Microarray, RT-qPCR	Perdaens et al. (2020)
	miR-124	Downregulated	RT-qPCR	Amoruso et al. (2020)
Peripheral blood	miR-146b, miR-21, miR-326, miR-142-3p, miR-155, miR-146a	Upregulated	RT-qPCR	Ma et al. (2014)
	miR-125a, miR-200c, miR-146b	Upregulated	Microarray analysis, RT-qPCR	Yang et al. (2014)
	miR-145	Upregulated	RT-qPCR	Søndergaard et al. (2013)
	miR-152	Downregulated	Microarray analysis, RT-qPCR	Yang et al. (2014)
	miR-15a, miR-15b, miR-328, miR-181c	Downregulated	RT-qPCR	Ma et al. (2014)
	miR-17, miR-20a	Downregulated	Microarray analysis, RT-qPCR	Cox et al. (2010)
Cerebrospinal fluid	miR-181c, miR-633	Upregulated	RT-qPCR	Haghikia et al. (2012)
	miR-15a-3p, miR-34c-5p	Downregulated	Microarray, RT-qPCR	Perdaens et al. (2020)
	miR-922	Downregulated	RT-qPCR	Haghikia et al. (2012)