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Summary of pharmacokinetics parameters (ng/mL)
| Cycle/Day | Parameter | Dose 1 0.7 mg (n=3) |
Dose 2 2.0 mg (n=3) |
Dose 3 7.0 mg (n=3) |
Dose 4 10.0 mg (n=3) |
|---|---|---|---|---|---|
| Cycle 1 | Cmax | ||||
| n | 0 | 0 | 1 | 3 | |
| Geometric Mean | NC | 330.6 | |||
| Geometric CV% | NC | 238.9 | |||
| Tmax | 0 | 0 | |||
| N | 1 | 3 | |||
| Median | NC | 0.27 | |||
| Min | NC | 0.25 | |||
| Max | NC | 0.27 |
CV% = Coefficient of variation; Min = Minimum; Max = Maximum; SD = Standard Deviation; NC = Not Calculable. n = number of PK evaluable patients
