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[Preprint]. 2024 Jun 5:rs.3.rs-4420617. [Version 1] doi: 10.21203/rs.3.rs-4420617/v1

Figure 4. Gata4 mRNA and protein are upregulated in the aortic root of LDS mice.

Figure 4.

(A) Representative images of RNA in situ hybridization for Gata4 in the aortic root and ascending aorta of control and LDS (Tgfbr1M318R/+) mice. Insets identify the location shown at higher magnification in the subsequent panel. Scale bars 50 and 200 microns, respectively. (B) Representative images of immunofluorescence for GATA4in the aortic root and ascending aorta of control and LDS mice. Insets identify the location shown at higher magnification in the subsequent panel. Scale bars 50 and 200 microns, respectively. (C) Immunoblot for Gata4 expression relative to ß-actin in aortic root lysates of control (n=3) and LDS mice (n=3), and related quantification of immunoblot, P-value refers to two-tailed Student’s t-test.