Figure 8. Smooth muscle-specific deletion of Gata4 results in reduced expression of Cebpb.

Representative images of RNA in situ hybridization for Cebpb in the aortic root of mice of indicated genotype at 16 weeks of age. Three independent biological replicates are shown per genotype abbreviated as follows Control (Tgfbr1^+/+) and LDS (Tgfbr1^M318R/+) with (Gata4^SMcKO) or without (Gata4^Ctrl) smooth muscle specific deletion of Gata4. Insets identify location shown at higher magnification in subsequent panels. Images were acquired at 20x magnification. Scale bars 50 and 200 microns, respectively.